Objective

Dig4Bio is a Twinning Action that aims to revolutionize the biomanufacturing landscape through digitalization, enhancing efficiency, reducing costs, and ensuring precise quality control in the production of biopharmaceuticals and advanced therapy modalities. This Twinning action is set to advance IST’s research capacity and profile in digital biomanufacturing, while also bolstering research management and administrative skills.

Overall methodology

A biomanufacturing process typically comprises a string of activities grouped in stages (upstream processing, downstream processing, fill & finish) that are designed and appropriately monitored and managed with the goal of producing a certain amount of a target product with specific quality attributes. By analogy, the workflow of the project Dig4Bio encompasses a series of activities that we group in three stages and manage with the ultimate goal of stepping up and stimulating scientific excellence and innovation capacity in digitalization of biomanufacturing, as well as the scientific quality of the partners involved. We will start with UPSTREAM training and capacitation activities (WP1 & WP2) and then build upon their outcomes to tackle a new research challenge and engage in clustering activities DOWNSTREAM (WP3 & WP4). The results of the research and of the project will be communicated and disseminated to stakeholders, scientific community and general public – FILL & FINISH (WP5 & WP6).

 

 

 

Work Packages

Dig4Bio spans 36 months and is structured around 6 interconnected Work Packages (WPs) that encompass various aspects of research, training, collaboration, and dissemination.

WP1

(Advancing scientific capacity) focus on enhancing the scientific and research management skills and knowledge of IST through specialised and tailored activities (13 workshops, 6 training schools, 3 digital tools, 12 short term visits).

Work Package 1

WP2

(Enhancing research management capacity) focus on enhancing the scientific and research management skills and knowledge of IST through specialised and tailored activities (13 workshops, 6 training schools, 3 digital tools, 12 short term visits).

Work Package 2

WP3

(Joint research activities) is the R&I component of Dig4Bio and aims at advancing knowledge in the field. IST, DTU and TUB will collaborate closely on a groundbreaking initiative designed to address the question: “How to develop and incorporate a digitalization framework in the conceptual design, research and development of biomanufacturing processes”.

Work Package 3

WP4

(Clustering activities) is dedicated to fostering close ties, synergies and knowledge exchange between the consortium members and stakeholders.

Work Package 4

WP5

(Communication and dissemination) aims to disseminate findings, engage with the scientific community, and promote awareness of advancements related to digitalization of biomanufacturing through various communication channels.

Work Package 5

WP6

(Coordination and management) provides the necessary administrative support to ensure the successful execution of all project components and that the project runs smoothly on time and within budget.

Work Package 6