Consistent Bioprocess Development

26-27 March 2026
Hybrid (link will follow), max 10 participants on-site & 20 online

OBJECTIVES

In this in hybrid workshop, methodology and model-based tools to ensure an efficient development of bioprocesses from high throughput to industrial scale.

COURSE LECTURORS

• Annina Kemmer, TU Berlin
• Fabian Schröder Kleeberg, TU Berlin
• Nicolas Cruz, TU Berlin
• Okyanus Yazgin, TU Berlin
• Peter Neubauer, TU Berlin
• Rosa Haßfurther, TU Berlin

REQUIREMENTS

Attendees must have the technical capability to join a Zoom call.
For the Exercise participants will install open source bioSTEAM: https://biosteam.readthedocs.io/en/latest/

Please contact Rosa Hassfurther (r.hassfurther@tu-berlin.de) if you experience problems.

PROGRAM

Day 1: Introduction to model-based Tools
Thursday – 26 March 2026 (CET time zone)

10:00 Opening remarks & Overview
10.10  Theory of Scale-up/Scale-down – Challenges and Sate of the art
12.00  Coffee break
12.20  Case study 1: Model-driven monitoring and scale-down of an E. coli Fed-batch process
13:00 Lunch break
14:00 Continuation Case Study 1
14:30 Coffee break
15:00  Basics on model-based Design of Experiment
16:30  Day 1 wrap-up

Day 2:  Lab Automation Software– Hands-on Experience
Friday – 27 March 2026 (CET time zone)

10:00  Welcome back
10:10   Case study 2: High throughput scale-down of an industrial pharmaceutical production process
11:00  Introduction to process flow sheet simulation
11:30  Coffee break 
11:50  Exercise with open source bioSTEAM
12.45  Lunch break
13:45 Continuation: bioSTEAM
15:00 Day 2 wrap-up